Rheumatoid arthritis is an autoimmune disease which occurs when the immune system mistakenly attacks its own tissues. It affects the joints of the knees. Unfortunately the joint effect is symmetrical which means if one knee is affected, the other is also. It leads to inflammation that thickens the synovium (tissue that lines the inside of joints) which can damage or destroy the bone and cartilage in the joint. It causes pain, swelling and stiffness. Genetic factors, environmental exposures and obesity may increase the risk of the disease which can occur at any age but most cases it appears between the ages of 40 and 60. There is no cure for RA, but remission of the symptoms is possible with treatments that contain medications such as steroids and disease-modifying antirheumatic drugs (DMARDs). Surgery is recommended when treatments are unable to relieve symptoms.
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